LYMPHOID NEOPLASIA Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome
نویسندگان
چکیده
Richard C. Harvey,1,2 Charles G. Mullighan,3 Xuefei Wang,1 Kevin K. Dobbin,4 George S. Davidson,5 Edward J. Bedrick,1 I-Ming Chen,1,2 Susan R. Atlas,1 Huining Kang,1 Kerem Ar,1 Carla S. Wilson,1 Walker Wharton,1 Maurice Murphy,1 Meenakshi Devidas,2,6 Andrew J. Carroll,6,7 Michael J. Borowitz,2,8 W. Paul Bowman,2,9 James R. Downing,3 Mary Relling,3 Jun Yang,3 Deepa Bhojwani,3 William L. Carroll,2,10 Bruce Camitta,2,11 Gregory H. Reaman,2,12 Malcolm Smith,13 Stephen P. Hunger,2,14 and Cheryl L. Willman1,2
منابع مشابه
Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia.
Acute lymphoblastic leukemia (ALL) is the commonest childhood malignancy and is characterized by recurring structural genetic alterations. Previous studies of DNA methylation suggest epigenetic alterations may also be important, but an integrated genome-wide analysis of genetic and epigenetic alterations in ALL has not been performed. We analyzed 137 B-lineage and 30 T-lineage childhood ALL cas...
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تاریخ انتشار 2010